# Purinergic signalling

Purinergic signalling (or signaling: see American and British English differences) is a form of extracellular signalling mediated bypurine nucleotides and nucleosides such as adenosine and ATP. It involves the activation of purinergic receptors in the cell and/or in nearby cells, thereby regulating cellular functions.[1]

The purinergic signalling complex of a cell is sometimes referred to as the “purinome”.